Endocrine Abstracts

A 42 year old lady was referred to the endocrine clinic with a five month history suggestive of hypothyroidism and a high TSH and low T4 levels. Clinical examination revealed increased skin pigmentation, low systemic blood pressure, bilateral axillary lymphadenopathy and hepatosplenomegaly. Short synacthen test confirmed cortisol insuffiency and she was started on thyroxine and hydrocortisone, and went on to have further investigations for the lymphadenopathy and hepatosplenom...

A32 year old lady was admitted with symptoms of palpitations, tremors, insomnia, heat intolerance, weight loss and excessive perspiration for 4 weeks. Worsening of these symptoms with vomiting prompted the admission. She had similar episode 7 yrs ago following the birth of her child when a provisional diagnosis of postpartum thyrotoxicosis was made but lost follow up with in 2 weeks. She works as a carer looking after mentally handicapped children. Her mother suffers from hypo...

We present the case of a 49 year old man who initially presented to his GP with complaints of tiredness, weight gain and tingling in his right hand. GP requested thyroid hormone measurements which showed FT4 level of 3.4 picomoles per litre and TSH 10.89 milli international units per litre. The inappropriately low TSH level raised the possibility of central hypothyroidism and triggered further investigations which revealed a low level for GH, LH, FSH, testosterone and cortisol...